dissolution enhancement of glybenclamide by solid dispersion technique
نویسندگان
چکیده
منابع مشابه
Enhancement of Dissolution Rate of Efavirenz by Solid Dispersion Technique
Efavirenz is an HIV-1 specific, non-nucleoside reverse transcriptase inhibitor (NNRTI).It is an antiretroviral agent indicated for the treatment of human immunodeficiency virus type 1 (HIV-1) infection, which is not soluble in water and lower absorption in gastric fluid. In order to improve the solubility and oral absorption of the drug in gastric fluid and to enhance its dissolution rate, soli...
متن کاملEnhancement of dissolution rate of etoricoxib through solid dispersion technique
Etoricoxib, a non-steroidal anti-inflammatory drug, is used to Osteoarthritis, Rheumatoid arthritis and Acute Gouty arthritis. Etoricoxib is practically insoluble in water; hence present study was carried out to enhance dissolution properties of Etoricoxib through the preparation of Solid Dispersions using PEG 6000 as carrier at various proportions by using different techniques like Physical mi...
متن کاملEnhancement of Dissolution Profile of Mefenamic Acid by Solid Dispersion Technique
The oral Bioavailability of BCS (Bio Pharmaceutical Classification System) class II drug with poor solubility and reasonable permeability is limited by drug dissolution. The purpose of this research was to obtain enhancement of the dissolution profile of Mefenamic acid (MA) using solid dispersion technique with hydrophilic polymers such as poly ethylene glycol (PEG), polyvinyl pyrrolidone (PVP)...
متن کاملEnhancement of dissolution profile for oral delivery of Fexofenadine Hydrochloride by solid dispersion (solvent evaporation) technique
The objective of present work is to investigate the enhancement of dissolution profile for oral delivery of Fexofenadine Hydrochloride (FH) through solid dispersion (SD) technique by the method of solvent evaporation. The SD was prepared by using ethanol as a solvent. Tablets were formulated containing solid dispersion of FH and compared with tablets of same formula without solid dispersion of ...
متن کاملDissolution study of Spironolactone by using solid dispersion technique
The main objective of the current study was to formulate poorly water soluble drug Spirinolactone by using solid dispersion technique in order to achieve a better dissolution rate which would further help in enhancing oral bioavailability. Solid dispersions were prepared using two methods; solvent method and fusion method. Solid dispersion was prepared by using polymers, such as Hydroxy propyly...
متن کاملStudies on dissolution enhancement of prednisolone, a poorly water-soluble drug by solid dispersion technique.
INTRODUCTION Prednisolone is a class II substance according to the Biopharmaceutics Classification System. It is a poorly water soluble agent. The aim of the present study was to improve dissolution rate of a poorly water-soluble drug, prednisolone, by a solid dispersion technique. METHODS Solid dispersion of prednisolone was prepared with PEG 6000 or different carbohydrates such as lactose a...
متن کاملمنابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
research in pharmaceutical sciencesجلد ۷، شماره ۵، صفحات ۰-۰
میزبانی شده توسط پلتفرم ابری doprax.com
copyright © 2015-2023